PCOS Ai

Can a Blood Test Diagnose PCOS? What Changed With AMH

By Alice, Founder, PCOS Ai · Updated 2026-08-10

For years, getting a PCOS diagnosis often meant a transvaginal ultrasound. The 2023 international guideline changed that for adults, and a lot of people have not heard.

The two-of-three diagnostic criteria for PCOSThe three diagnostic criteria for PCOS in adults, any two of which are needed. The third can be met by ultrasound or a raised AMH blood test. Meeting the first two means neither is required.In adults, diagnosis needs any two of these three1Signs of excess androgensvisible, or on bloods2Irregular or absent ovulation3Polycystic ovaries on ultrasoundor a raised AMH — this is what changedMeet the first two, and the guideline says neither scan nor AMH is required.Plenty of people have waited months for a scan they did not need.
Any two of the three. The third line is the one the 2023 guideline changed.

How PCOS is diagnosed

In adults, diagnosis needs two of these three, once other causes have been ruled out:

That third line is what changed. AMH — anti-Müllerian hormone — is a blood test, and the 2023 guideline accepts it as an alternative to ultrasound in adults. The evidence had been building since the previous edition, and the panel judged it strong enough.

The part more people should know

If you have both irregular cycles and signs of excess androgens, you already meet two of the three criteria. In that case the guideline says ultrasound and AMH are not required at all.

Plenty of people have waited months for a scan they did not need. If that is your situation, it is a fair question to put to your doctor.

Why this matters beyond convenience

A transvaginal ultrasound is invasive, and for some people — those who have not been sexually active, anyone with a history of assault, or people who simply find it distressing — it is a real barrier to getting diagnosed at all. A blood draw is not the same thing.

It also removes a scheduling bottleneck. A blood test is easier to get than a scan in most healthcare systems, and delayed diagnosis is one of the most consistent complaints people with PCOS report.

Where AMH does not apply

Two important limits:

AMH is also used in fertility clinics as a rough marker of ovarian reserve. The same number is being read for a different purpose there, which is a common source of confusion.

What to ask

Thyroid problems and raised prolactin can produce a similar picture, and both are simple blood tests. "Other causes excluded" is part of the criteria, not an optional extra.

Bring evidence, not recollection

Two of the three criteria depend on things you observe rather than things a lab measures. "My cycles are irregular" is much stronger with dates attached, and so is a record of when acne or unwanted hair changed.

PCOS Ai keeps that record and turns it into a summary you can hand over, so the appointment starts from your actual history. Our appointment guide covers what else is worth taking, and how long is too long between periods covers what counts as irregular.

Sources

Keep reading

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